ChemicalBook > CAS DataBase List > 2,2,2-Trifluoroethyl trifluoromethanesulfonate

2,2,2-Trifluoroethyl trifluoromethanesulfonate

Product Name
2,2,2-Trifluoroethyl trifluoromethanesulfonate
CAS No.
6226-25-1
Chemical Name
2,2,2-Trifluoroethyl trifluoromethanesulfonate
Synonyms
2,2,2-TRIFLUOROETHYL TRIFLUOROMETHANESULPHONATE;2,2,2-TRIFLUOROETHYL TRIFLATE;TFOL-TF;2,2,2-Trifluoroethyl Triflante;2,2,2-Trifluoroethyl trifluoromethanesulf;2-Trifluoroethyl trifluoromethanesulfonate;2,2,2-Trifluoroethytrifluoromethanesulfonate;2,2,2-Trifluoroethyl trifluoromethanesulfote;2,2,2-Trifluoroethyl trifluoroMethylsulfonate;2,2,2-TRIFLUOROETHYL TRIFLUOROMETHANESULFONATE
CBNumber
CB5142808
Molecular Formula
C3H2F6O3S
Formula Weight
232.1
MOL File
6226-25-1.mol
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2,2,2-Trifluoroethyl trifluoromethanesulfonate Property

Boiling point:
89-91°C
Density 
1,61 g/cm3
refractive index 
1.3037
RTECS 
PB2775000
Flash point:
>110°(230°F)
storage temp. 
2-8°C
solubility 
Chloroform, Methanol (Slightly)
form 
Liquid
color 
Colorless to yellow
Water Solubility 
Slightly soluble in water.
Sensitive 
Moisture Sensitive
InChIKey
RTMMSCJWQYWMNK-UHFFFAOYSA-N
CAS DataBase Reference
6226-25-1(CAS DataBase Reference)
EPA Substance Registry System
Methanesulfonic acid, trifluoro-, 2,2,2-trifluoroethyl ester (6226-25-1)
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Safety

Hazard Codes 
Xi,T,C
Risk Statements 
36/37/38-34-23/25
Safety Statements 
26-36/37/39-45
RIDADR 
3265
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
TOXIC, CORROSIVE
HazardClass 
8
PackingGroup 
HS Code 
29055900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H314Causes severe skin burns and eye damage

H330Fatal if inhaled

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
752924
Product name
2,2,2-Trifluoroethyl trifluoromethanesulfonate
Purity
95%
Packaging
5g
Price
$135
Updated
2024/03/01
TCI Chemical
Product number
T1604
Product name
2,2,2-Trifluoroethyl Trifluoromethanesulfonate
Purity
>97.0%(GC)
Packaging
5g
Price
$142
Updated
2024/03/01
TCI Chemical
Product number
T1604
Product name
2,2,2-Trifluoroethyl Trifluoromethanesulfonate
Purity
>97.0%(GC)
Packaging
25g
Price
$354
Updated
2024/03/01
Alfa Aesar
Product number
H61603
Product name
2,2,2-Trifluoroethyl trifluoromethanesulfonate, 95%
Packaging
5g
Price
$128.65
Updated
2024/03/01
Alfa Aesar
Product number
H61603
Product name
2,2,2-Trifluoroethyl trifluoromethanesulfonate, 95%
Packaging
25g
Price
$462.65
Updated
2024/03/01
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2,2,2-Trifluoroethyl trifluoromethanesulfonate Chemical Properties,Usage,Production

Uses

A fluorine-containing alkyl alkanesulfonate with cyctotoxity towards cultured leukemia L1210 cells.

Uses

2,2,2-Trifluoroethyl trifluoromethanesulfonate is a powerful trifluoroethylating agent which is useful for synthesis of fluorinated amino acids. It is used as a reagent in thenantioselective preparation of cyclic N-aryl hydroxamic acids via phase-transfer catalyzed alkylation of nitrobenzyl bromides to give nirophenylalanines.

Uses

Reagent used in thenantioselective preparation of cyclic N-aryl hydroxamic acids via phase-transfer catalyzed alkylation of nitrobenzyl bromides to give nirophenylalanines

Synthesis

In a 100-ml flask equipped with a stirrer, a thermometer, a nitrogen introducing pipe, and a condenser, 50 ml (0.297 mol) of trifluoromethane sulfonic anhydride and 25 ml (0.342 moles) of 2,2,2-trifluoroethanol were placed at room temperature and stirred for 30 minutes in a nitrogen atmosphere, followed by reflux for 3 hours. After distillation, 50.3 g of 2,2,2-trifluoroethyl trifluoromethanesulfonate was obtained in a yield of 73%.

2,2,2-Trifluoroethyl trifluoromethanesulfonate Preparation Products And Raw materials

Raw materials

Preparation Products

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2,2,2-Trifluoroethyl trifluoromethanesulfonate Suppliers

Alfa Chemistry
Tel
+1-5166625404
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
21317
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63711
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58
Aceschem Inc.
Tel
+1-817863-6948 +1-(817)863-6948
Email
sales@aceschem.com
Country
United States
ProdList
19639
Advantage
58
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View Lastest Price from 2,2,2-Trifluoroethyl trifluoromethanesulfonate manufacturers

LY Global chemicals co.,ltd .
Product
2,2,2-Trifluoroethyl trifluoromethanesulfonate 6226-25-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000KG
Release date
2023-03-09
Henan Aochuang Chemical Co.,Ltd.
Product
2,2,2-Trifluoroethyl trifluoromethanesulfonate 6226-25-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-09
Zhuozhou Wenxi import and Export Co., Ltd
Product
2,2,2-Trifluoroethyl Trifluoromethanesulfonate 6226-25-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

6226-25-1, 2,2,2-Trifluoroethyl trifluoromethanesulfonateRelated Search:


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